STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH10960.1KEGG: fre:Franean1_1141 hypothetical protein. (243 aa)    
Predicted Functional Partners:
mutM
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.761
AEH09675.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.668
AEH10963.1
Fatty acid synthesis plsX protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
     0.592
AEH10272.1
KEGG: fri:FraEuI1c_2426 hypothetical protein.
  
     0.559
AEH11574.1
KEGG: fra:Francci3_4285 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide repeat.
  
     0.544
rnc
Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
       0.539
rpmF-2
TIGRFAM: Ribosomal protein L32p; HAMAP: Ribosomal protein L32p; KEGG: fre:Franean1_1137 50S ribosomal protein L32; PFAM: Ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family.
       0.534
AEH10965.1
PFAM: Protein of unknown function DUF177; KEGG: fre:Franean1_1136 hypothetical protein.
       0.534
AEH09549.1
PFAM: Coagulation factor 5/8 type, C-terminal; KEGG: fra:Francci3_1050 hypothetical protein.
  
     0.511
AEH11665.1
Von Willebrand factor type A; KEGG: rcu:RCOM_1583660 protein binding protein, putative; PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A.
 
     0.497
Your Current Organism:
Frankia symbiont
NCBI taxonomy Id: 656024
Other names: F. symbiont of Datisca glomerata, Frankia symbiont of Datisca glomerata
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