D5GAF1_TUBMM protein (Tuber melanosporum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

D5GAF1_TUBMM

Uncharacterized protein. (451 aa)

Predicted Functional Partners:

GET1

0.553

D5GP16_TUBMM

0.543

D5G6C0_TUBMM

0.489

NOP7

0.475

GET3

0.451

D5GPH8_TUBMM

0.412

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G6C0_TUBMM	D5GAF1_TUBMM	D5G6C0	D5GAF1	Ipi1_N domain-containing protein.	Uncharacterized protein.	0.489
D5G6C0_TUBMM	D5GP16_TUBMM	D5G6C0	D5GP16	Ipi1_N domain-containing protein.	Uncharacterized protein.	0.999
D5G6C0_TUBMM	NOP7	D5G6C0	D5GH60	Ipi1_N domain-containing protein.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.897
D5GAF1_TUBMM	D5G6C0_TUBMM	D5GAF1	D5G6C0	Uncharacterized protein.	Ipi1_N domain-containing protein.	0.489
D5GAF1_TUBMM	D5GP16_TUBMM	D5GAF1	D5GP16	Uncharacterized protein.	Uncharacterized protein.	0.543
D5GAF1_TUBMM	D5GPH8_TUBMM	D5GAF1	D5GPH8	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.412
D5GAF1_TUBMM	GET1	D5GAF1	D5G451	Uncharacterized protein.	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.553
D5GAF1_TUBMM	GET3	D5GAF1	D5GGF4	Uncharacterized protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.451
D5GAF1_TUBMM	NOP7	D5GAF1	D5GH60	Uncharacterized protein.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.475
D5GP16_TUBMM	D5G6C0_TUBMM	D5GP16	D5G6C0	Uncharacterized protein.	Ipi1_N domain-containing protein.	0.999
D5GP16_TUBMM	D5GAF1_TUBMM	D5GP16	D5GAF1	Uncharacterized protein.	Uncharacterized protein.	0.543
D5GP16_TUBMM	D5GPH8_TUBMM	D5GP16	D5GPH8	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.744
D5GP16_TUBMM	NOP7	D5GP16	D5GH60	Uncharacterized protein.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.955
D5GPH8_TUBMM	D5GAF1_TUBMM	D5GPH8	D5GAF1	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.412
D5GPH8_TUBMM	D5GP16_TUBMM	D5GPH8	D5GP16	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.744
D5GPH8_TUBMM	NOP7	D5GPH8	D5GH60	Uncharacterized protein; Belongs to the DEAD box helicase family.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.998
GET1	D5GAF1_TUBMM	D5G451	D5GAF1	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	Uncharacterized protein.	0.553
GET1	GET3	D5G451	D5GGF4	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.997
GET3	D5GAF1_TUBMM	D5GGF4	D5GAF1	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Uncharacterized protein.	0.451
GET3	GET1	D5GGF4	D5G451	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.997