STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D5GC45_TUBMMRibosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (496 aa)    
Predicted Functional Partners:
D5G595_TUBMM
Importin N-terminal domain-containing protein.
    
   0.947
D5GBZ7_TUBMM
Importin subunit alpha; Belongs to the importin alpha family.
    
   0.947
D5GNX1_TUBMM
Brix domain-containing protein.
   
   0.879
D5GE52_TUBMM
RRM domain-containing protein.
   
   0.867
D5GCV2_TUBMM
Brix domain-containing protein.
   
   0.865
D5GLW0_TUBMM
Uncharacterized protein.
   
   0.865
D5GMC4_TUBMM
Uncharacterized protein.
   
 
 0.859
D5GLK5_TUBMM
SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.853
D5GHR8_TUBMM
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
   0.850
D5G6Z6_TUBMM
PUM-HD domain-containing protein.
   
 
 0.845
Your Current Organism:
Tuber melanosporum
NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28
Server load: low (20%) [HD]