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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJP59953.2Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)    
Predicted Functional Partners:
AJP58582.1
TIGR02099 family protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.721
tldD
Metalloprotease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.676
UC34_00740
GntR family transcriptional regulator; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the agmatine deiminase family.
  
 0.531
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
 0.517
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.495
glnE
Transposase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which i [...]
     
 0.490
APD11163.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.478
AJP60051.2
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.404
Your Current Organism:
Pandoraea vervacti
NCBI taxonomy Id: 656178
Other names: CCM 7667, DSM 23571, NBRC 106088, P. vervacti, Pandoraea sp. NS15, Pandoraea vervacti Sahin et al. 2011, strain NS15
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