STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mhpA3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). (613 aa)    
Predicted Functional Partners:
mhpB
3-(2,3-dihydroxyphenyl)propionate dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
 
 0.990
AJP56083.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.925
AJP56368.1
FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.923
AJP60044.1
2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.789
AJP58409.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.577
AJP58044.1
Cytochrome; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
 
 
 0.573
AJP60043.1
Transcriptional regulator; Activator of 3-phenylpropionic acid catabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.560
mhpC
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid.
 
  
 0.523
APD11163.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.492
AJP59688.2
Phosphatidylserine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphatidylserine decarboxylase family.
  
   
 0.488
Your Current Organism:
Pandoraea vervacti
NCBI taxonomy Id: 656178
Other names: CCM 7667, DSM 23571, NBRC 106088, P. vervacti, Pandoraea sp. NS15, Pandoraea vervacti Sahin et al. 2011, strain NS15
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