| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKM29964.1 | AKM30067.1 | AB870_07370 | AB870_08085 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.809 |
| AKM29964.1 | glmU | AB870_07370 | AB870_12980 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.923 |
| AKM29964.1 | lpxA | AB870_07370 | AB870_21550 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.865 |
| AKM29964.1 | mrdB | AB870_07370 | AB870_12375 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.673 |
| AKM29964.1 | murA | AB870_07370 | AB870_09485 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.914 |
| AKM29964.1 | murB | AB870_07370 | AB870_06480 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.937 |
| AKM29964.1 | murC | AB870_07370 | AB870_08555 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.449 |
| AKM30067.1 | AKM29964.1 | AB870_08085 | AB870_07370 | Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.809 |
| AKM30067.1 | murA | AB870_08085 | AB870_09485 | Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.809 |
| AKM30067.1 | murB | AB870_08085 | AB870_06480 | Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.902 |
| AKM30067.1 | murC | AB870_08085 | AB870_08555 | Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.807 |
| AKM30282.1 | hisD | AB870_09470 | AB870_09475 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.783 |
| AKM30282.1 | hisG | AB870_09470 | AB870_09480 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.783 |
| AKM30282.1 | murA | AB870_09470 | AB870_09485 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.783 |
| glmU | AKM29964.1 | AB870_12980 | AB870_07370 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
| glmU | lpxA | AB870_12980 | AB870_21550 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.862 |
| glmU | murA | AB870_12980 | AB870_09485 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.939 |
| glmU | murC | AB870_12980 | AB870_08555 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.578 |
| hisD | AKM30282.1 | AB870_09475 | AB870_09470 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.783 |
| hisD | hisG | AB870_09475 | AB870_09480 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.996 |