Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (212 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.958
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.955
ALO67867.1
Pyrimidine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.945
ALO66754.1
Ribose-5-phosphate isomerase; Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.922
pyrR
Transcriptional regulator; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
    
 0.910
ALO65211.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.908
ALO65756.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HAD-like hydrolase superfamily.
    
  0.902
rihB
Ribonucleoside hydrolase; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.900
ALO66969.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.814
tadA
Cytidine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
 
 0.768
Your Current Organism:
Arthrobacter alpinus
NCBI taxonomy Id: 656366
Other names: A. alpinus, Arthrobacter alpinus Zhang et al. 2010, Arthrobacter sp. A3, Arthrobacter sp. S6-3, CGMCC 1.8950, DSM 22274, strain S6-3
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