Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
AS189_01315Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)    
Predicted Functional Partners:
ALO67618.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.663
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.657
ALO65380.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.549
ALO66332.1
Pilus assembly protein TadE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.537
ALO65382.1
Secretion system protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.507
ALO65184.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.485
ALO66422.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.464
ALO65383.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.460
ALO65700.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.451
ALO68211.1
Lipopolysaccharide kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.448
Your Current Organism:
Arthrobacter alpinus
NCBI taxonomy Id: 656366
Other names: A. alpinus, Arthrobacter alpinus Zhang et al. 2010, Arthrobacter sp. A3, Arthrobacter sp. S6-3, CGMCC 1.8950, DSM 22274, strain S6-3
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