STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALO65414.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)    
Predicted Functional Partners:
gyrB
DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.857
ALO65413.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.765
ALO68404.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.680
ALO68245.1
RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.584
ALO66742.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.511
ALO65632.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.492
ALO65663.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.487
ALO65838.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.475
ALO67262.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.471
ALO65412.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.455
Your Current Organism:
Arthrobacter alpinus
NCBI taxonomy Id: 656366
Other names: A. alpinus, Arthrobacter alpinus Zhang et al. 2010, Arthrobacter sp. A3, Arthrobacter sp. S6-3, CGMCC 1.8950, DSM 22274, strain S6-3
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