STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALO68311.1Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)    
Predicted Functional Partners:
ALO65797.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.982
ALO65808.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.977
ALO65810.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.937
ALO65605.1
Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.610
ALO66700.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.538
ALO65812.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.516
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 
 0.467
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.431
ALO68189.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.428
ALO65811.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.417
Your Current Organism:
Arthrobacter alpinus
NCBI taxonomy Id: 656366
Other names: A. alpinus, Arthrobacter alpinus Zhang et al. 2010, Arthrobacter sp. A3, Arthrobacter sp. S6-3, CGMCC 1.8950, DSM 22274, strain S6-3
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