STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALO66216.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (79 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.997
ALO66770.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.984
ALO68378.1
Glycine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.966
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.958
ALO66222.1
Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...]
  
 
 0.827
ALO65702.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.717
ALO66239.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.695
ALO68551.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.585
ALO65890.1
Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.579
ALO67847.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.557
Your Current Organism:
Arthrobacter alpinus
NCBI taxonomy Id: 656366
Other names: A. alpinus, Arthrobacter alpinus Zhang et al. 2010, Arthrobacter sp. A3, Arthrobacter sp. S6-3, CGMCC 1.8950, DSM 22274, strain S6-3
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.