| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALO65317.1 | ALO67393.1 | AS189_00940 | AS189_13970 | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.814 |
| ALO65317.1 | ALO67496.1 | AS189_00940 | AS189_14610 | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | 0.913 |
| ALO65317.1 | ALO67917.1 | AS189_00940 | AS189_17305 | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.803 |
| ALO65317.1 | kgd | AS189_00940 | AS189_07460 | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.946 |
| ALO65317.1 | sucC | AS189_00940 | AS189_17765 | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.933 |
| ALO65317.1 | sucD | AS189_00940 | AS189_17760 | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.923 |
| ALO67393.1 | ALO65317.1 | AS189_13970 | AS189_00940 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.814 |
| ALO67393.1 | ALO67496.1 | AS189_13970 | AS189_14610 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | 0.801 |
| ALO67393.1 | ALO67876.1 | AS189_13970 | AS189_17060 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.581 |
| ALO67393.1 | ALO67877.1 | AS189_13970 | AS189_17065 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.578 |
| ALO67393.1 | ALO67917.1 | AS189_13970 | AS189_17305 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
| ALO67393.1 | kgd | AS189_13970 | AS189_07460 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.775 |
| ALO67393.1 | sucC | AS189_13970 | AS189_17765 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.921 |
| ALO67393.1 | sucD | AS189_13970 | AS189_17760 | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.928 |
| ALO67496.1 | ALO65317.1 | AS189_14610 | AS189_00940 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
| ALO67496.1 | ALO67393.1 | AS189_14610 | AS189_13970 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.801 |
| ALO67496.1 | ALO67917.1 | AS189_14610 | AS189_17305 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.816 |
| ALO67496.1 | sucC | AS189_14610 | AS189_17765 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.906 |
| ALO67496.1 | sucD | AS189_14610 | AS189_17760 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.920 |
| ALO67874.1 | ALO67875.1 | AS189_17050 | AS189_17055 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |