STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADQ13539.1Phosphonopyruvate decarboxylase; KEGG: cbe:Cbei_4337 thiamine pyrophosphate binding domain-containing protein; TIGRFAM: phosphonopyruvate decarboxylase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein. (377 aa)    
Predicted Functional Partners:
ADQ13538.1
Phosphoenolpyruvate phosphomutase; KEGG: cbe:Cbei_4338 cytidyltransferase-like protein; TIGRFAM: phosphoenolpyruvate phosphomutase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase.
 
 0.998
ADQ13540.1
Hypothetical protein; KEGG: pdi:BDI_1465 hemolysin erythrocyte lysis protein 2.
 
     0.948
ADQ14852.1
KEGG: hor:Hore_10840 acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.
  
 
 0.881
ADQ13541.1
PFAM: iron-containing alcohol dehydrogenase; KEGG: bfr:BF2576 putative alcohol dehydrogenase.
 
   
 0.819
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.594
ADQ15738.1
KEGG: hor:Hore_20820 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein.
  
  
 0.559
ilvD
TIGRFAM: dihydroxy-acid dehydratase; KEGG: hor:Hore_10820 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
  
 0.541
ADQ13981.1
KEGG: hmo:HM1_1037 glutamate synthase [nadph] large chain; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein.
  
  
 0.540
ADQ13619.1
PFAM: aminotransferase class IV; KEGG: cno:NT01CX_0378 4-amino-4-deoxychorismate lyase.
  
 
 0.467
ADQ13743.1
TIGRFAM: branched-chain amino acid aminotransferase; KEGG: cac:CA_C1479 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV.
  
 
 0.467
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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