Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ13592.1PFAM: protein of unknown function DUF1312; KEGG: amt:Amet_0355 hypothetical protein. (140 aa)    
Predicted Functional Partners:
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
     0.692
purC
KEGG: dhd:Dhaf_0799 phosphoribosylaminoimidazolesuccinocarboxamide synthase; PFAM: SAICAR synthetase.
       0.678
ADQ14555.1
PFAM: Heptaprenyl diphosphate synthase component I; KEGG: hor:Hore_14270 heptaprenyl diphosphate synthase component I.
 
    0.659
ADQ15024.1
KEGG: hor:Hore_09210 putative membrane fusion protein.
  
     0.555
ADQ14727.1
Protein of unknown function DUF6 transmembrane; KEGG: hor:Hore_08620 predicted permease, DMT superfamily; manually curated; PFAM: protein of unknown function DUF6 transmembrane.
  
     0.451
ADQ15125.1
PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: hor:Hore_13330 positive regulator of sigma E, RseC/MucC.
 
     0.446
ADQ13594.1
Hypothetical protein; KEGG: dha:DEHA2G05082g DEHA2G05082p.
       0.441
ADQ15723.1
PFAM: Ferritin Dps family protein; KEGG: amt:Amet_3466 ferritin, Dps family protein; Belongs to the Dps family.
  
     0.441
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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