STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ13679.1Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; GAF domain protein; metal-dependent phosphohydrolase HD sub domain; KEGG: nth:Nther_2187 diguanylate cyclase and metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region. (898 aa)    
Predicted Functional Partners:
ADQ13683.1
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; response regulator receiver; KEGG: glo:Glov_1550 multi-sensor hybrid histidine kinase; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.985
ADQ14324.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: cth:Cthe_0408 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein.
 
 0.902
ADQ13998.1
Signal transduction histidine kinase, LytS; KEGG: bbe:BBR47_58750 two-component hybrid sensor and regulator; PFAM: histidine kinase internal region; response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein.
  
 
 0.860
ADQ14501.1
Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; response regulator receiver; PAS fold domain protein; metal-dependent phosphohydrolase HD sub domain; KEGG: kol:Kole_0452 diguanylate cyclase and metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region.
 
 
0.844
ADQ13913.1
Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; metal-dependent phosphohydrolase HD sub domain; KEGG: pth:PTH_0546 hypothetical protein; SMART: GGDEF domain containing protein; GAF domain protein; PAS domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region.
 
 
0.835
ADQ14006.1
Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold domain protein; metal-dependent phosphohydrolase HD sub domain; KEGG: nth:Nther_0783 diguanylate cyclase and metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PAS domain containing protein; metal-dependent phosphohydrolase HD region.
 
 
0.829
ADQ14503.1
Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; metal-dependent phosphohydrolase HD sub domain; KEGG: nth:Nther_0783 diguanylate cyclase and metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region.
 
 
0.826
ADQ14595.1
KEGG: kko:Kkor_0171 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein.
 
 0.805
ADQ13590.1
KEGG: nth:Nther_2186 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer.
 
 
 0.717
ADQ15707.1
Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; metal-dependent phosphohydrolase HD sub domain; KEGG: amt:Amet_0967 diguanylate cyclase and metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PAS domain containing protein; metal-dependent phosphohydrolase HD region.
 
 
0.698
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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