Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ13688.1TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: abu:Abu_2317 GGDEF/PAS domain-containing protein; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. (842 aa)    
Predicted Functional Partners:
ADQ13683.1
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; response regulator receiver; KEGG: glo:Glov_1550 multi-sensor hybrid histidine kinase; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
0.908
ADQ14324.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: cth:Cthe_0408 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein.
 
 0.897
ADQ14595.1
KEGG: kko:Kkor_0171 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein.
 
 0.866
ADQ13739.1
Putative PAS/PAC sensor protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; PAS fold-4 domain protein; KEGG: dth:DICTH_1580 putative response regulator; SMART: metal-dependent phosphohydrolase HD region; GAF domain protein.
 
 
 0.798
ADQ13976.1
TIGRFAM: PAS sensor protein; PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; KEGG: dth:DICTH_1580 putative response regulator; SMART: metal-dependent phosphohydrolase HD region; PAS domain containing protein.
  
 
 0.760
ADQ14294.1
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; KEGG: sat:SYN_00099 two-component response regulator; SMART: metal-dependent phosphohydrolase HD region.
  
 
 0.756
ADQ13998.1
Signal transduction histidine kinase, LytS; KEGG: bbe:BBR47_58750 two-component hybrid sensor and regulator; PFAM: histidine kinase internal region; response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein.
  
 
 0.727
ADQ14200.1
KEGG: nth:Nther_2059 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
  
 
 0.711
ADQ14006.1
Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold domain protein; metal-dependent phosphohydrolase HD sub domain; KEGG: nth:Nther_0783 diguanylate cyclase and metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PAS domain containing protein; metal-dependent phosphohydrolase HD region.
 
 
0.700
ADQ14503.1
Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; metal-dependent phosphohydrolase HD sub domain; KEGG: nth:Nther_0783 diguanylate cyclase and metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region.
 
 
0.699
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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