Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ14182.1PFAM: PfkB domain protein; KEGG: afl:Aflv_2784 fructokinase (ribokinase family); Belongs to the carbohydrate kinase PfkB family. (314 aa)    
Predicted Functional Partners:
ADQ13520.1
KEGG: amt:Amet_0828 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system EIIC.
     
 0.925
ADQ14927.1
TIGRFAM: 1-phosphofructokinase; KEGG: gbm:Gbem_3234 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.916
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: hor:Hore_19060 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.911
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
 0.910
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
   
 0.909
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
   
 0.909
ADQ14194.1
TIGRFAM: mannose-6-phosphate isomerase, class I; KEGG: cac:CA_C2918 mannose-6 phospate isomelase; PFAM: mannose-6-phosphate isomerase type I.
    
 0.906
ADQ13746.1
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: det:DET0125 alcohol dehydrogenase, zinc-containing.
  
 
 0.904
fbp
Fructose-bisphosphatase; KEGG: cno:NT01CX_1512 fructose-1,6-bisphosphatase; PFAM: fructose-16-bisphosphatase.
    
 0.901
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.900
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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