Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa)    
Predicted Functional Partners:
ADQ14289.1
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: gct:GC56T3_3077 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.999
pgk
KEGG: hor:Hore_15820 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 0.999
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: hor:Hore_19060 glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 0.991
ADQ13859.1
TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: hor:Hore_18020 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II.
 
 0.987
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.984
ADQ14127.1
Transketolase; KEGG: hor:Hore_14410 transketolase; TIGRFAM: transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; Belongs to the transketolase family.
  
 0.959
ADQ14543.1
Transketolase; KEGG: hor:Hore_14410 transketolase; TIGRFAM: transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; Belongs to the transketolase family.
  
 0.959
ADQ15234.1
KEGG: hor:Hore_03220 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
 
 
 0.954
ADQ13786.1
PFAM: fructose-bisphosphate aldolase class-I; KEGG: oih:OB3245 fructose-1,6-bisphosphate aldolase.
   
 0.946
ADQ13790.1
PFAM: fructose-bisphosphate aldolase class-I; KEGG: oih:OB3245 fructose-1,6-bisphosphate aldolase.
   
 0.946
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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