Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ14319.1PFAM: Lipoprotein LpqB, GerMN domain; KEGG: hor:Hore_15500 hypothetical protein. (179 aa)    
Predicted Functional Partners:
ADQ14318.1
N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: hor:Hore_15510 N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin.
       0.793
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
    0.736
ADQ14322.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.731
ADQ14317.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; KEGG: hor:Hore_07420 multi-sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein.
       0.714
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.710
ADQ14314.1
PFAM: ABC-2 type transporter; KEGG: mac:MA4320 hypothetical protein.
       0.570
ADQ14315.1
Hypothetical protein; KEGG: pyo:PY04167 mature-parasite-infected erythrocyte surface antigen.
       0.570
ADQ14316.1
KEGG: mba:Mbar_A0600 gliding motility protein; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.570
ADQ13858.1
KEGG: hor:Hore_18030 hypothetical protein.
  
     0.520
ADQ14560.1
TIGRFAM: rod shape-determining protein MreD; KEGG: hor:Hore_14220 hypothetical protein.
  
     0.493
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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