Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ14379.1PFAM: 5'-Nucleotidase domain-containing protein; KEGG: cdf:CD2537 putative membrane-associated 5'-nucleotidase/phosphoesterase. (221 aa)    
Predicted Functional Partners:
ADQ14378.1
PFAM: metallophosphoesterase; KEGG: amt:Amet_3610 5'-nucleotidase domain-containing protein.
     0.989
ADQ15708.1
PFAM: metallophosphoesterase; 5'-Nucleotidase domain-containing protein; KEGG: nph:NP1854A 5'-nucleotidase 1; 2',3'-cyclic-nucleotide 2'-phosphodiesterase 1; UDP-sugar hydrolase 1; Belongs to the 5'-nucleotidase family.
 
     0.830
ADQ13980.1
TIGRFAM: glycerate kinase; KEGG: hor:Hore_22950 glycerate kinase; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
 
 
    0.722
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.565
deoD
KEGG: cno:NT01CX_2329 purine nucleoside phosphorylase; TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1.
    
 0.526
ADQ14808.1
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
  0.516
ADQ14380.1
Sigma54 specific transcriptional regulator, Fis family; KEGG: cbi:CLJ_B3468 sigma-54 dependent transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase.
       0.447
ADQ14381.1
PFAM: histidine biosynthesis protein; flavoprotein; KEGG: mmb:Mmol_0896 flavoprotein; Belongs to the HisA/HisF family.
       0.447
ADQ14382.1
PFAM: dihydropteroate synthase DHPS; KEGG: nhl:Nhal_0006 dihydropteroate synthase DhpS.
       0.447
ADQ14383.1
PFAM: protein of unknown function DUF447; KEGG: meh:M301_0952 protein of unknown function DUF447.
       0.447
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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