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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
ADQ14381.1PFAM: histidine biosynthesis protein; flavoprotein; KEGG: mmb:Mmol_0896 flavoprotein; Belongs to the HisA/HisF family. (426 aa)    
Predicted Functional Partners:
ADQ14384.1
KEGG: mei:Msip34_1505 beta-ribofuranosylaminobenzene 5'-phosphate synthase family; TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinase; GHMP kinase domain protein.
 
    0.959
ADQ14383.1
PFAM: protein of unknown function DUF447; KEGG: meh:M301_0952 protein of unknown function DUF447.
 
     0.955
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.950
ADQ14382.1
PFAM: dihydropteroate synthase DHPS; KEGG: nhl:Nhal_0006 dihydropteroate synthase DhpS.
 
     0.947
hisA
TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: llc:LACR_1328 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein.
  
  
0.937
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
  0.918
hisI
phosphoribosyl-ATP diphosphatase; KEGG: tex:Teth514_1007 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; In the N-terminal section; belongs to the PRA-CH family.
     
  0.900
ADQ14390.1
KEGG: mfs:MFS40622_0802 formylmethanofuran dehydrogenase subunit A; TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3.
 
   
 0.877
ffsA
Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
     0.869
ADQ14399.1
PFAM: aspartate/glutamate/uridylate kinase; KEGG: mpd:MCP_0670 putative amino acid kinase.
 
     0.867
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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