STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ14406.1TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: tpd:Teth39_0501 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (425 aa)    
Predicted Functional Partners:
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.989
ADQ15132.1
PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: ctc:CTC01806 5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.954
ADQ14734.1
PFAM: aminotransferase class I and II; KEGG: cth:Cthe_2800 aminotransferase, class I and II.
   
 0.931
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.917
ADQ14621.1
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; KEGG: hor:Hore_08020 homoserine dehydrogenase.
  
 
 0.848
ADQ14743.1
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: pmo:Pmob_1153 homoserine dehydrogenase.
  
 
 0.848
ADQ15139.1
KEGG: gka:GK1525 cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.846
ADQ15747.1
KEGG: hor:Hore_23060 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.846
ADQ15530.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aco:Amico_0198 pyridoxal-5'-phosphate-dependent protein beta subunit.
  
 
 0.835
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
    
  0.814
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.