Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ14410.1KEGG: dev:DhcVS_199 membrane protein, Hly III family; TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. (209 aa)    
Predicted Functional Partners:
ADQ14411.1
RNA polymerase, sigma 54 subunit, RpoN; KEGG: tte:TTE1764 DNA-directed RNA polymerase specialized sigma subunits, sigma54 homologs; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor; sigma-54 factor core-binding region.
       0.668
msrA
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.551
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.490
deoD
KEGG: cno:NT01CX_2329 purine nucleoside phosphorylase; TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1.
       0.470
ADQ14582.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.400
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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