Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ14423.1KEGG: mma:MM_1318 hypothetical protein; PFAM: CBS domain containing protein; peptidase M50; SMART: CBS domain containing protein; Belongs to the peptidase M50B family. (378 aa)    
Predicted Functional Partners:
ADQ14424.1
Signal transduction histidine kinase, LytS; PFAM: Transcription regulator,histidine kinase sensor-like; histidine kinase internal region; ATP-binding region ATPase domain protein; KEGG: tjr:TherJR_0614 histidine kinase.
       0.693
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.600
ADQ14892.1
PHP domain protein; KEGG: hor:Hore_05670 DNA polymerase X family protein; PFAM: PHP domain protein; DNA polymerase beta domain protein region; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein.
 
    0.595
ADQ15440.1
TIGRFAM: phosphoribosylformylglycinamidine synthase; KEGG: tjr:TherJR_0822 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
     
 0.527
ADQ14425.1
KEGG: tjr:TherJR_0615 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver.
       0.512
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.480
ADQ14926.1
KEGG: tgr:Tgr7_0290 ATPase, P-type (transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase.
 
    0.463
ADQ14779.1
PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: scl:sce7466 TrkA family potassium uptake protein.
 
     0.452
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.436
glgA
Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
  
    0.435
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.