STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ14949.1KEGG: hor:Hore_10930 PhoH family protein; PFAM: PhoH family protein; SMART: Nucleotide binding protein PINc. (437 aa)    
Predicted Functional Partners:
ADQ14948.1
KEGG: hor:Hore_10950 SpoIID/LytB domain protein; TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation protein D.
  
    0.733
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.630
ADQ14950.1
PFAM: protein of unknown function DUF296; KEGG: tit:Thit_0241 protein of unknown function DUF296.
       0.623
ADQ14568.1
Manually curated; TIGRFAM: ribonuclease, Rne/Rng family; KEGG: hor:Hore_14130 ribonuclease, Rne/Rng family; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; deoxyribonuclease/rho motif-related TRAM.
  
    0.480
ADQ14947.1
Membrane protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
       0.442
ADQ14952.1
KEGG: hor:Hore_10780 hypothetical protein; Belongs to the 5'(3')-deoxyribonucleotidase family.
       0.436
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
  
     0.412
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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