Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ15450.1PFAM: NLPA lipoprotein; KEGG: hor:Hore_22280 NlpA lipoprotein; Belongs to the nlpA lipoprotein family. (284 aa)    
Predicted Functional Partners:
ADQ15451.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: hor:Hore_22290 binding-protein-dependent transport systems inner membrane component.
 0.999
metN
ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
 0.998
ADQ14406.1
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: tpd:Teth39_0501 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
  
    0.670
ADQ15449.1
PFAM: protein of unknown function DUF1232; KEGG: hor:Hore_22250 protein of unknown function (DUF1232).
       0.470
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.451
ADQ15134.1
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: cbi:CLJ_B1732 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.405
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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