Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ15553.1KEGG: hor:Hore_18960 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (590 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
  
 0.927
ADQ15552.1
PFAM: protein of unknown function DUF374; KEGG: hor:Hore_18950 hypothetical protein.
 
     0.779
ADQ15554.1
PFAM: HutP family protein; KEGG: hor:Hore_18970 HutP family protein.
       0.773
ADQ15548.1
KpsF/GutQ family protein; SMART: CBS domain containing protein; TIGRFAM: KpsF/GutQ family protein; KEGG: hor:Hore_18910 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.727
kdsA
KEGG: hor:Hore_18920 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA.
 
   
 0.637
ADQ15547.1
PFAM: lipid A biosynthesis acyltransferase; KEGG: hor:Hore_18900 lipid A biosynthesis lauroyl acyltransferase.
 
  
 0.616
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.613
ADQ15546.1
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.596
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
     
 0.587
ADQ13936.1
PFAM: permease YjgP/YjgQ family protein; KEGG: hor:Hore_17610 permease YjgP/YjgQ family protein.
 
  
 0.576
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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