Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ15586.1PFAM: amidohydrolase; KEGG: pmo:Pmob_1730 dihydropyrimidinase. (463 aa)    
Predicted Functional Partners:
pyrB
TIGRFAM: aspartate carbamoyltransferase; KEGG: hor:Hore_09370 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.996
carA
KEGG: drm:Dred_1683 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family.
  
 0.979
ADQ13794.1
TIGRFAM: amidase, hydantoinase/carbamoylase family; KEGG: lsg:lse_0451 amidase, hydantoinase/carbamoylase family protein; PFAM: peptidase M20; peptidase dimerisation domain protein.
 
 
 0.958
ADQ15515.1
KEGG: pmo:Pmob_1743 dihydroorotate dehydrogenase family protein; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate oxidase.
 
 
 0.934
carB-2
KEGG: tjr:TherJR_1830 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family.
 
 0.915
carB
KEGG: sat:SYN_02589 carbamoyl phosphate synthase large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family.
 
 
 0.854
pyrF
TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: hor:Hore_09390 orotidine-5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.842
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.840
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.770
ADQ15527.1
KEGG: cbl:CLK_2276 peptidase; TIGRFAM: M20/DapE family protein YgeY; PFAM: peptidase M20; peptidase dimerisation domain protein.
 
  
 0.769
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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