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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (253 aa)    
Predicted Functional Partners:
ADQ15601.1
KEGG: tte:TTE0381 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein.
 
 
 0.996
cobT
Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.984
ADQ15616.1
PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: taf:THA_1039 cob(I)yrinic acid a,c-diamide adenosyltransferase.
 
 
 0.969
ADQ15609.1
KEGG: tit:Thit_0358 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
  
  
 0.962
ADQ14438.1
TIGRFAM: ATP/cobalamin adenosyltransferase; KEGG: kol:Kole_0446 ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.927
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.914
cobQ-2
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.914
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.909
ADQ15608.1
KEGG: tmt:Tmath_0429 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK.
  
  
 0.855
ADQ15610.1
TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: amt:Amet_0074 precorrin-4 C11-methyltransferase; PFAM: anaerobic cobalt chelatase; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.846
Your Current Organism:
Halanaerobium hydrogeniformans
NCBI taxonomy Id: 656519
Other names: H. hydrogeniformans, Halanaerobium sapolanicus, strain SL-HP
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