STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
SMB93521.1glutaconyl-CoA decarboxylase beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (392 aa)    
Predicted Functional Partners:
SMB84626.1
Pyruvate carboxylase subunit B; InterPro IPR000891:IPR003379:IPR000089:IPR001882:IPR005776; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; KEGG: hch:HCH_06704 pyruvate carboxylase subunit B; SPTR: B5IWM5 Oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; TIGRFAM: oxaloacetate decarboxylase alpha subunit.
 
 0.999
SMB93510.1
Biotin-requiring enzyme; InterPro IPR000089:IPR001882; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; KEGG: sfu:Sfum_0461 conserved carboxylase region; SPTR: Q9ZAA7 Glutaconyl-CoA decarboxylase subunit gamma; PFAM: biotin/lipoyl attachment domain-containing protein.
 
  
 0.978
SMB93490.1
Sodium pump decarboxylases, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family.
  
 0.961
SMB83330.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...]
    
 0.897
SMB93482.1
methylmalonyl-CoA decarboxylase alpha subunit; InterPro IPR000022:IPR011762:IPR011763; COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); KEGG: dal:Dalk_3780 propionyl-CoA carboxylase; SPTR: A1HP30 Carboxyl transferase; PFAM: carboxyl transferase.
  
 
 0.896
SMB92300.1
Malate dehydrogenase (oxaloacetate-decarboxylating); InterPro IPR001891:IPR012302:IPR012301; COGs: COG0281 Malic enzyme; KEGG: dds:Ddes_1534 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SPTR: O34962 Probable NAD-dependent malic enzyme 4; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating).
    
 0.753
SMB82978.1
TIGRFAM: pyruvate kinase; InterPro IPR015793:IPR008279:IPR015794:IPR018209:IPR001697; COGs: COG0469 Pyruvate kinase; KEGG: dps:DP3116 pyruvate kinase; SPTR: P80885 Pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
     
 0.737
SMB89755.1
PRIAM: Pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; InterPro IPR008279:IPR002192:IPR000121:IPR018274:IPR010121; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; KEGG: bba:Bd1150 pyruvate phosphate dikinase; SPTR: A2UA87 Pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; Belongs to the PEP-utilizing enzyme family.
    
 0.730
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
    
 0.726
SMB90274.1
Pyruvate, water dikinase; InterPro IPR008279:IPR002192; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; KEGG: scl:sce4177 phosphoenolpyruvate synthase; SPTR: Q466P7 Phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PRIAM: Pyruvate, water dikinase.
    
 0.725
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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