STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB93696.1Peptidase family M48; InterPro IPR010432; KEGG: sbp:Sbal223_0113 peptidase M48 Ste24p; SPTR: P42401 Uncharacterized protein yckC; PFAM: RDD domain containing protein. (253 aa)    
Predicted Functional Partners:
SMB80869.1
SPTR: A2UAQ3 Dynamin; KEGG: hypothetical protein.
 
   0.695
SMB80870.1
Small GTP-binding protein domain-containing protein; InterPro IPR001401:IPR002917; KEGG: hypothetical protein; SPTR: A2UAQ3 Dynamin; PFAM: Dynamin family protein; GTP-binding protein HSR1-related.
 
   0.681
msrA
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.644
SMB82236.1
Flagellar motor switch protein FliM; InterPro IPR001689:IPR001172:IPR001543; COGs: COG1868 Flagellar motor switch protein; KEGG: wsu:WS1638 flagellar motor switch protein FliM; SPTR: A1HN28 Flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; TIGRFAM: flagellar motor switch protein FliM.
    
   0.609
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
  
 0.605
SMB92264.1
Tetratricopeptide repeat-containing protein; InterPro IPR001440:IPR013105:IPR019734:IPR013026; COGs: COG3063 Tfp pilus assembly protein PilF; KEGG: TPR Domain containing protein; SPTR: Q24CU0 TPR Domain containing protein; SMART: Tetratricopeptide repeat; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein.
  
  
 0.466
SMB87089.1
Protein of unknown function; SPTR: O06998 Uncharacterized protein yvdQ.
  
     0.465
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 
 0.453
SMB96279.1
ATP-dependent metalloprotease FtsH; InterPro IPR000642:IPR003959:IPR003593:IPR003960; COGs: COG0465 ATP-dependent Zn protease; KEGG: FTSH1; membrane AAA-metalloprotease (EC:3.4.24.-); K03798 cell division protease FtsH; SPTR: A1HLY1 Vesicle-fusing ATPase; SMART: AAA ATPase; PFAM: AAA ATPase central domain protein; peptidase M41; PRIAM: Vesicle-fusing ATPase; Belongs to the AAA ATPase family.
   
 
 0.453
SMB82268.1
Flagellar basal-body rod protein FlgG; InterPro IPR001444:IPR010930:IPR020013; COGs: COG4786 Flagellar basal body rod protein; KEGG: hch:HCH_04085 flagellar basal body rod protein; SPTR: P0A1J3 Flagellar basal-body rod protein flgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; TIGRFAM: fagellar hook-basal body protein.
    
   0.450
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.