STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB94896.1COGs: COG0142 Geranylgeranyl pyrophosphate synthase; KEGG: gsu:GSU1765 geranyltranstransferase; SPTR: Q5ISD9 Geranylgeranyl diphosphate synthase; PFAM: Polyprenyl synthetase; InterPro IPR000092; Belongs to the FPP/GGPP synthase family. (298 aa)    
Predicted Functional Partners:
xseA
Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
 
  
 0.948
SMB94007.1
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.898
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
 
 0.895
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
  
 0.881
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
  
 0.873
SMB94915.1
23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase; InterPro IPR002877:IPR002942:IPR004538; COGs: COG1189 rRNA methylase; SPTR: A1HQ59 Hemolysin A; SMART: RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: gur:Gura_2037 hemolysin A; TIGRFAM: hemolysin A.
 
    0.841
SMB83317.1
Undecaprenyl diphosphate synthase; InterPro IPR001441:IPR000560; COGs: COG0020 Undecaprenyl pyrophosphate synthase; KEGG: vsa:VSAL_I2423 undecaprenyl pyrophosphate synthetase; SPTR: Q8TPS4 Di-trans-poly-cis-decaprenylcistransferase; PFAM: Di-trans-poly-cis-decaprenylcistransferase.
 
 
 0.810
SMB94884.1
Sulfide dehydrogenase (flavoprotein) subunit SudA; InterPro IPR000759:IPR013027:IPR000103:IPR001327:IPR006004; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; KEGG: sat:SYN_00606 glutamate synthase (NADPH); SPTR: A1HTT3 Glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric.
    
 0.808
SMB94873.1
Sulfide dehydrogenase (flavoprotein) subunit SudB; InterPro IPR008333:IPR001433:IPR019480; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; KEGG: sat:SYN_00607 ferredoxin-NADP(+) reductase subunit alpha; SPTR: Q9V047 Putative uncharacterized protein; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain.
       0.792
SMB94898.1
Hypothetical protein; InterPro IPR003832; COGs: COG1963 conserved hypothetical protein; KEGG: hypothetical protein; SPTR: A0ZAD2 Acid phosphatase/vanadium-dependent haloperoxidase-like protein; PFAM: acid phosphatase/vanadium-dependent haloperoxidase related.
       0.792
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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