STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
SMB95604.1Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (136 aa)    
Predicted Functional Partners:
SMB95610.1
Uncharacterized protein, UPF0297 family; InterPro IPR009309; COGs: COG4472 conserved hypothetical protein; SPTR: Q8RAH3 UPF0297 protein TTE1249; PFAM: protein of unknown function DUF965; Belongs to the UPF0297 family.
  
    0.942
SMB95602.1
Protein of unknown function; InterPro IPR009711; KEGG: hypothetical protein LOC766249; SPTR: B0TFZ1 UPF0473 protein Helmi_02360; PFAM: protein of unknown function DUF1292; Belongs to the UPF0473 family.
  
    0.889
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.824
SMB95606.1
Predicted oxidoreductase; InterPro IPR020471:IPR001395:IPR001450:IPR017900; COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); KEGG: gbm:Gbem_2501 aldo/keto reductase; SPTR: A1HU99 Aldo/keto reductase; PFAM: aldo/keto reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein.
       0.737
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
    0.647
mltG
UPF0755 protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.548
SMB95588.1
Predicted O-methyltransferase YrrM; InterPro IPR002935; COGs: COG4122 O-methyltransferase; KEGG: wol:WD1057 O-methyltransferase family protein; SPTR: A5KMV7 Putative uncharacterized protein; PFAM: O-methyltransferase family 3.
 
     0.544
SMB84402.1
23S rRNA (guanosine2251-2'-O)-methyltransferase; InterPro IPR001537:IPR013123:IPR004441; COGs: COG0566 rRNA methylase; KEGG: ppg:PputGB1_4935 RNA methyltransferase; SPTR: A3IGG2 23S rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; TIGRFAM: RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
    0.533
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
     
 0.488
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.404
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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