STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB88493.1SH3 domain-containing protein; InterPro IPR010466:IPR013247:IPR003646; KEGG: hypothetical protein; SPTR: A9U795 Predicted protein (Fragment); SMART: SH3 domain protein; PFAM: SH3 type 3 domain protein; protein of unknown function DUF1058. (220 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.768
cinA
Nicotinamide-nucleotide amidase; InterPro IPR001453:IPR008136:IPR008135; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; KEGG: dds:Ddes_1466 competence/damage-inducible protein CinA; SPTR: A6M320 Putative competence-damage inducible protein; PFAM: CinA domain protein; molybdopterin binding domain; TIGRFAM: competence/damage-inducible protein CinA.
    
  0.725
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.705
SMB89084.1
LysM domain-containing protein; InterPro IPR002477:IPR018392:IPR002482; KEGG: mxa:MXAN_0560 penicillin-resistant dd-carboxypeptidase; SPTR: A0YYN1 Peptidoglycan-binding domain 1 protein; SMART: Peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding domain 1 protein; Peptidoglycan-binding lysin domain.
    
 0.579
SMB88503.1
InterPro IPR003856; KEGG: nam:NAMH_1653 chain length determinant protein; SPTR: A2UBX9 Lipopolysaccharide biosynthesis; PFAM: lipopolysaccharide biosynthesis protein.
 
     0.528
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
       0.482
SMB88486.1
UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; PFAM: Glycosyl transferase, family 4, conserved region; InterPro IPR018481:IPR018480; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; KEGG: geo:Geob_2139 phospho-N-acetylmuramoyl-pentapeptide-transferase; SPTR: A2UBL3 Glycosyl transferase, family 4.
       0.482
SMB91000.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
  0.482
SMB88511.1
G-rich domain on putative tyrosine kinase; KEGG: bam:Bamb_5116 exopolysaccharide transport protein family; SPTR: P33698 Succinoglycan biosynthesis transport protein exoP.
       0.453
SMB88723.1
InterPro IPR002797; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; KEGG: cha:CHAB381_0962 virulence factor MviN family protein; SPTR: A3ICA0 Polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein.
  
     0.452
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.