STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB79233.1InterPro IPR000160; COGs: COG2199 FOG: GGDEF domain; KEGG: vfi:VF_1245 GGDEF domain-containing protein; SPTR: A4BIU7 Response regulator containing a CheY-like receiver domain and a GGDEF domain; SMART: GGDEF domain containing protein; PFAM: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase. (296 aa)    
Predicted Functional Partners:
SMB88249.1
Diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR001633:IPR000160:IPR003660; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; KEGG: bph:Bphy_0391 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SPTR: A4U5J6 Putative uncharacterized protein; SMART: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; PFAM: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; TIGRFAM: diguanylate cyclase.
 0.990
SMB87902.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR013655:IPR000160:IPR013656:IPR000014; COGs: COG2199 FOG: GGDEF domain; KEGG: tau:Tola_1998 diguanylate cyclase with PAS/PAC sensor and hemerythrin-like metal-binding domain; SPTR: A3JDG3 Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); SMART: GGDEF domain containing protein; PAS domain containing protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; TIGRFAM: diguanylate cyclase; PAS sens [...]
0.984
SMB79451.1
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant); InterPro IPR001633; COGs: COG2200 FOG: EAL domain; KEGG: abu:Abu_0830 EAL domain-containing protein; SPTR: A2U9Q9 Diguanylate phosphodiesterase; SMART: EAL domain protein; PFAM: EAL domain protein.
 
 0.982
SMB95186.1
Diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR006674:IPR003660:IPR003607; COGs: COG2206 HD-GYP domain; KEGG: ppr:PBPRA1970 hypothetical protein; SPTR: Q0W2L1 Putative signal transduction protein; SMART: GGDEF domain containing protein; metal-dependent phosphohydrolase HD region; histidine kinase HAMP region domain protein; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; histidine kinase HAMP region domain protein; TIGRFAM: diguanylate cyclase.
0.981
SMB79879.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR013655:IPR000160:IPR006674:IPR013767:IPR001610:IPR0036 07:IPR000014:IPR000700; COGs: COG2206 HD-GYP domain; KEGG: pin:Ping_0273 diguanylate cyclase with PAS/PAC sensor; SPTR: A0YVN1 PleD-like protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region; PAS domain containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; metal-dependent phosphohyd [...]
0.979
SMB82971.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR006674:IPR013656:IPR001610:IPR000700:IPR0000 14; COGs: COG2206 HD-GYP domain; KEGG: tdn:Suden_0219 multi-sensor hybrid histidine kinase; SPTR: A1HLT0 Metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; PAS fold-4 domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein.
0.979
SMB89764.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR013656:IPR013767:IPR001610:IPR000014:IPR0007 00; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; KEGG: bja:bll1362 hypothetical protein; SPTR: A0YMH5 PleD-like protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein.
 
0.976
SMB80928.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR013655:IPR000160:IPR000700:IPR000014; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; KEGG: pag:PLES_03351 putative sensory box protein; SPTR: A3L087 Putative uncharacterized protein; SMART: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein.
 
 
0.966
SMB91698.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR007892:IPR006674:IPR003607:IPR000014:IPR0007 00; COGs: COG2206 HD-GYP domain; KEGG: dps:DP2126 hypothetical protein; SPTR: Q0W2L1 Putative signal transduction protein; SMART: GGDEF domain containing protein; metal-dependent phosphohydrolase HD region; PAS domain containing protein; PFAM: GGDEF domain containing protein; CHASE4 domain protein; metal-dependent phosphohydrolase HD sub domain; TIGRFAM: diguanylate cyclase; PAS sensor protein.
0.963
SMB79906.1
HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant); InterPro IPR006674:IPR003607; COGs: COG2206 HD-GYP domain; KEGG: pst:PSPTO_1152 HDIG domain-containing protein; SPTR: A1HNK6 Metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region; PFAM: metal-dependent phosphohydrolase HD sub domain.
 0.958
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.