node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMB80175.1 | SMB93408.1 | SAMN00017405_0843 | SAMN00017405_0030 | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | NusB antitermination factor; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.670 |
SMB80175.1 | gatA | SAMN00017405_0843 | SAMN00017405_0840 | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.763 |
SMB80175.1 | gatB | SAMN00017405_0843 | SAMN00017405_0839 | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. | 0.719 |
SMB80175.1 | gatC | SAMN00017405_0843 | SAMN00017405_0841 | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.759 |
SMB80175.1 | ligA | SAMN00017405_0843 | SAMN00017405_0842 | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.949 |
SMB80175.1 | polA | SAMN00017405_0843 | SAMN00017405_2122 | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.783 |
SMB80175.1 | topA | SAMN00017405_0843 | SAMN00017405_0122 | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.611 |
SMB80175.1 | uvrC | SAMN00017405_0843 | SAMN00017405_1648 | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.759 |
SMB83330.1 | gatC | SAMN00017405_1028 | SAMN00017405_0841 | Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...] | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.745 |
SMB83330.1 | leuS | SAMN00017405_1028 | SAMN00017405_0854 | Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...] | leucyl-tRNA synthetase; InterPro IPR002302:IPR015413:IPR013155:IPR002300:IPR001412; COGs: COG0495 Leucyl-tRNA synthetase; KEGG: gme:Gmet_2300 leucyl-tRNA synthetase; SPTR: Q2RKZ1 Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.800 |
SMB83330.1 | ligA | SAMN00017405_1028 | SAMN00017405_0842 | Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...] | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.758 |
SMB83330.1 | polA | SAMN00017405_1028 | SAMN00017405_2122 | Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.401 |
SMB83330.1 | topA | SAMN00017405_1028 | SAMN00017405_0122 | Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.934 |
SMB93408.1 | SMB80175.1 | SAMN00017405_0030 | SAMN00017405_0843 | NusB antitermination factor; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | 0.670 |
SMB93408.1 | gatA | SAMN00017405_0030 | SAMN00017405_0840 | NusB antitermination factor; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.626 |
SMB93408.1 | gatB | SAMN00017405_0030 | SAMN00017405_0839 | NusB antitermination factor; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. | 0.666 |
SMB93408.1 | ligA | SAMN00017405_0030 | SAMN00017405_0842 | NusB antitermination factor; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.853 |
SMB93408.1 | polA | SAMN00017405_0030 | SAMN00017405_2122 | NusB antitermination factor; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.676 |
SMB93408.1 | topA | SAMN00017405_0030 | SAMN00017405_0122 | NusB antitermination factor; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.645 |
gatA | SMB80175.1 | SAMN00017405_0840 | SAMN00017405_0843 | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | ATP-dependent DNA helicase PcrA; InterPro IPR000212:IPR014016:IPR014017:IPR005751; COGs: COG0210 Superfamily I DNA and RNA helicase; KEGG: gur:Gura_4326 UvrD/REP helicase; SPTR: O34580 ATP-dependent DNA helicase pcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA. | 0.763 |