STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
SMB82259.1CheR methyltransferase, SAM binding domain; InterPro IPR000780; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; KEGG: bra:BRADO2290 putative chemotaxis protein methyltransferase; SPTR: A1HMK5 MCP methyltransferase, CheR-type; SMART: MCP methyltransferase CheR-type; PFAM: MCP methyltransferase CheR-type. (143 aa)    
Predicted Functional Partners:
cheB
Two-component system, chemotaxis family, response regulator CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.978
SMB96633.1
Two-component system, chemotaxis family, sensor kinase CheA; InterPro IPR004358:IPR008207:IPR004105:IPR010808:IPR002545:IPR0035 94:IPR005467; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; KEGG: nam:NAMH_0362 chemotaxis protein CheA; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; PFAM: P2 response regulator binding domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; ATP-binding region ATPase domain protein; SPTR: A1HMP8 CheA signal transduction histidine kinases.
 
 
 0.973
SMB82225.1
Flagellar motor switch protein FliN/FliY; InterPro IPR001172:IPR001543:IPR007597:IPR012826; COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; KEGG: sde:Sde_2174 surface presentation of antigens (SpoA) protein; SPTR: A2U857 CheC, inhibitor of MCP methylation; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; TIGRFAM: flagellar motor switch protein FliN.
 
 
 0.970
SMB82254.1
Chemotaxis protein CheC; InterPro IPR007597; COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; KEGG: gme:Gmet_3210 CheC, inhibitor of MCP methylation; SPTR: A1HN13 CheC, inhibitor of MCP methylation; PFAM: CheC domain protein.
 
  
 0.950
SMB82263.1
CheR methyltransferase, all-alpha domain; InterPro IPR000780; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; KEGG: pca:Pcar_2491 methylase of chemotaxis methyl-accepting proteins, CheR-like; SPTR: Q9KCB8 Chemotaxis protein methyltransferase.
     0.950
cheD
Chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  
 0.949
SMB81810.1
InterPro IPR002545; COGs: COG0835 Chemotaxis signal transduction protein; KEGG: dvm:DvMF_0284 CheW protein; SPTR: O29218 Purine-binding chemotaxis protein (CheW); SMART: CheW domain protein; PFAM: CheW domain protein.
 
 
 0.937
SMB82249.1
Two-component system, chemotaxis family, response regulator CheY; InterPro IPR001789; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; KEGG: mxa:MXAN_6693 fibril biogenesis regulator DifD; SPTR: A1HN26 Response regulator receiver protein; SMART: response regulator receiver; PFAM: response regulator receiver.
 
 
 0.935
SMB78753.1
Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor; InterPro IPR004090:IPR004089:IPR018247:IPR000700:IPR000014; COGs: COG0840 Methyl-accepting chemotaxis protein; KEGG: dde:Dde_1279 methyl-accepting chemotaxis sensory transducer; SPTR: Q3IQX3 Transducer protein htr25; SMART: chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; TIGRFAM: PAS sensor protein.
 
 0.931
SMB78920.1
Methyl-accepting chemotaxis protein; InterPro IPR004090:IPR004089:IPR003660; COGs: COG0840 Methyl-accepting chemotaxis protein; KEGG: vfm:VFMJ11_A0131 methyl-accepting chemotaxis protein; SPTR: Q8TUP6 Methyl-accepting chemotaxis protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
 
 0.926
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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