STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB83163.1tRNA(Ile)-lysidine synthase TilS/MesJ; InterPro IPR011063; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; KEGG: gbm:Gbem_0615 PP-loop domain protein; SPTR: A5KLL2 Putative uncharacterized protein; PFAM: PP-loop domain protein; Belongs to the TtcA family. (242 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.837
SMB87745.1
Uncharacterized protein; InterPro IPR011063:IPR018317:IPR005232; KEGG: gur:Gura_3906 PP-loop domain-containing protein; SPTR: A1HPZ1 ExsB family protein; PFAM: PP-loop domain protein; Queuosine synthesis-like; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily.
 
    0.827
SMB87325.1
Sulfur carrier protein; InterPro IPR003749:IPR010035; KEGG: cak:Caul_2567 thiamine biosynthesis protein ThiS; SPTR: Q2W3R9 Thiazole biosynthesis protein thiG; PFAM: thiamineS protein; TIGRFAM: thiamine biosynthesis protein ThiS.
  
 
 0.730
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.709
SMB96642.1
InterPro IPR000644:IPR010766:IPR004097; COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; KEGG: gsu:GSU2975 putative manganese-dependent inorganic pyrophosphatase; SMART: CBS domain containing protein; PFAM: DHHA2 domain protein; CBS domain containing protein; DRTGG domain protein; PRIAM: Inorganic diphosphatase; SPTR: A1HME9 Inorganic diphosphatase.
    
  0.705
SMB91517.1
InterPro IPR000836:IPR002375:IPR005904; COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; KEGG: hprT; hypoxanthine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase; SPTR: A1HRR9 Hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.578
SMB83157.1
Processive 1,2-diacylglycerol beta-glucosyltransferase; InterPro IPR001296:IPR009695; COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; KEGG: bur:Bcep18194_B0550 monogalactosyldiacylglycerol synthase; SPTR: A1HN53 Monogalactosyldiacylglycerol synthase; PFAM: Monogalactosyldiacylglycerol synthase; glycosyl transferase group 1.
       0.562
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.552
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.535
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
  
 0.526
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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