STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB83202.1Adapter protein MecA 1/2; InterPro IPR008681; COGs: COG4862 Negative regulator of genetic competence sporulation and motility; SPTR: A5KQX5 Putative uncharacterized protein; PFAM: Negative regulator of genetic competence. (218 aa)    
Predicted Functional Partners:
clpB
ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
    
 
 0.856
SMB84508.1
ATP-dependent Clp protease ATP-binding subunit ClpC; InterPro IPR001270:IPR001943:IPR003959:IPR019489:IPR013093:IPR0117 04:IPR004176:IPR003593:IPR018368; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; KEGG: CLPC; CLPC (HEAT SHOCK PROTEIN 93-V); ATP binding / ATPase; SPTR: Q8EU05 Chaperone protein clpB; SMART: AAA ATPase; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; AAA ATPase central domain protein; UvrB/UvrC protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; Belongs to the ClpA/ClpB family.
    
 
 0.856
SMB86930.1
Regulator of replication initiation timing; InterPro IPR010377; COGs: COG4467 conserved hypothetical protein; SPTR: Q81JB2 Initiation-control protein yabA; PFAM: protein of unknown function DUF972.
  
     0.589
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.579
SMB83093.1
InterPro IPR000644:IPR000524:IPR010766; COGs: COG4109 transcriptional regulator protein containing CBS domains; KEGG: hypothetical protein; K00088 IMP dehydrogenase; SPTR: A3I937 Putative uncharacterized protein; SMART: CBS domain containing protein; PFAM: DRTGG domain protein; CBS domain containing protein; regulatory protein GntR HTH.
  
    0.543
SMB83217.1
Hypothetical protein; InterPro IPR004173:IPR013196; COGs: COG1827 small molecule binding protein (contains 3H domain); KEGG: xau:Xaut_2380 helix-turn-helix type 11 domain-containing protein; SPTR: A1HQE1 Transcriptional regulator, Fis family; PFAM: 3H domain protein; Helix-turn-helix type 11 domain protein.
       0.528
msrA
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.479
SMB92677.1
Spore coat protein, CotS family; InterPro IPR014255; KEGG: choline kinase; SPTR: O34656 Spore coat protein I; TIGRFAM: spore coat protein, CotS family.
  
     0.475
SMB96451.1
InterPro IPR006343; KEGG: hypothetical protein; TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region.
  
     0.442
rnz
RNAse Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
 
     0.441
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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