STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB86160.1Ca2+-transporting ATPase; InterPro IPR000695:IPR001757:IPR006068:IPR008250:IPR005834:IPR0040 14:IPR018303; COGs: COG0474 Cation transport ATPase; KEGG: sat:SYN_01009 calcium-transporting ATPase; SPTR: A4E9R0 Putative uncharacterized protein; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; PRIAM: Calcium-transporting ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC. (864 aa)    
Predicted Functional Partners:
SMB96642.1
InterPro IPR000644:IPR010766:IPR004097; COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; KEGG: gsu:GSU2975 putative manganese-dependent inorganic pyrophosphatase; SMART: CBS domain containing protein; PFAM: DHHA2 domain protein; CBS domain containing protein; DRTGG domain protein; PRIAM: Inorganic diphosphatase; SPTR: A1HME9 Inorganic diphosphatase.
    
  0.811
coaX
Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.757
SMB86167.1
COGs: COG4684 membrane protein; SPTR: A5KPV1 Putative uncharacterized protein.
       0.686
SMB86169.1
Biotin transport system substrate-specific component; InterPro IPR003784; COGs: COG1268 conserved hypothetical protein; KEGG: BioY family protein; SPTR: P22819 Probable biotin transporter bioY; PFAM: BioY protein.
       0.563
tlp
InterPro IPR017524; KEGG: hypothetical protein; SPTR: A5I0M6 Protein tlp homolog; TIGRFAM: small, acid-soluble spore protein tlp; Belongs to the Tlp family.
       0.516
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.474
atpD
ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
   
 0.454
SMB94049.1
Putative Mg2+ transporter-C (MgtC) family protein; InterPro IPR003416; COGs: COG1285 membrane protein; KEGG: gme:Gmet_1981 MgtC/SapB transporter; SPTR: A1HSR5 MgtC/SapB transporter; PFAM: MgtC/SapB transporter.
  
 
 0.449
SMB89038.1
Protein of unknown function; KEGG: dat:HRM2_21160 hypothetical protein; SPTR: A2STV3 Putative uncharacterized protein.
  
 
 0.449
atpH
ATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
  0.426
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
Server load: low (24%) [HD]