STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
SMB90274.1Pyruvate, water dikinase; InterPro IPR008279:IPR002192; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; KEGG: scl:sce4177 phosphoenolpyruvate synthase; SPTR: Q466P7 Phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PRIAM: Pyruvate, water dikinase. (864 aa)    
Predicted Functional Partners:
SMB83330.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...]
    
 0.955
pgi
InterPro IPR001672; COGs: COG0166 Glucose-6-phosphate isomerase; KEGG: gur:Gura_3752 glucose-6-phosphate isomerase; SPTR: Q24VW9 Glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.943
SMB84626.1
Pyruvate carboxylase subunit B; InterPro IPR000891:IPR003379:IPR000089:IPR001882:IPR005776; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; KEGG: hch:HCH_06704 pyruvate carboxylase subunit B; SPTR: B5IWM5 Oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; TIGRFAM: oxaloacetate decarboxylase alpha subunit.
  
 
 0.940
SMB82978.1
TIGRFAM: pyruvate kinase; InterPro IPR015793:IPR008279:IPR015794:IPR018209:IPR001697; COGs: COG0469 Pyruvate kinase; KEGG: dps:DP3116 pyruvate kinase; SPTR: P80885 Pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
    
 0.917
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.916
SMB95186.1
Diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR006674:IPR003660:IPR003607; COGs: COG2206 HD-GYP domain; KEGG: ppr:PBPRA1970 hypothetical protein; SPTR: Q0W2L1 Putative signal transduction protein; SMART: GGDEF domain containing protein; metal-dependent phosphohydrolase HD region; histidine kinase HAMP region domain protein; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; histidine kinase HAMP region domain protein; TIGRFAM: diguanylate cyclase.
    
 0.870
SMB86303.1
Fructose-bisphosphate aldolase; InterPro IPR000771:IPR011289; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; KEGG: dds:Ddes_0131 fructose-1,6-bisphosphate aldolase, class II; SPTR: A1Z6B9 Putative fructose-1,6-bisphosphate aldolase class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase.
 
 
 0.869
SMB92300.1
Malate dehydrogenase (oxaloacetate-decarboxylating); InterPro IPR001891:IPR012302:IPR012301; COGs: COG0281 Malic enzyme; KEGG: dds:Ddes_1534 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SPTR: O34962 Probable NAD-dependent malic enzyme 4; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating).
  
 
 0.862
SMB79879.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR013655:IPR000160:IPR006674:IPR013767:IPR001610:IPR0036 07:IPR000014:IPR000700; COGs: COG2206 HD-GYP domain; KEGG: pin:Ping_0273 diguanylate cyclase with PAS/PAC sensor; SPTR: A0YVN1 PleD-like protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region; PAS domain containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; metal-dependent phosphohyd [...]
    
  0.858
SMB82971.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR006674:IPR013656:IPR001610:IPR000700:IPR0000 14; COGs: COG2206 HD-GYP domain; KEGG: tdn:Suden_0219 multi-sensor hybrid histidine kinase; SPTR: A1HLT0 Metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; PAS fold-4 domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein.
    
  0.858
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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