STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Coexpression
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[Homology]
Score
argHArgininosuccinate lyase; InterPro IPR000362:IPR009049; COGs: COG0165 Argininosuccinate lyase; KEGG: gur:Gura_0231 argininosuccinate lyase; SPTR: A4J174 Argininosuccinate lyase; PFAM: fumarate lyase; TIGRFAM: argininosuccinate lyase. (459 aa)    
Predicted Functional Partners:
argG
Argininosuccinate synthase; InterPro IPR001518:IPR018223; COGs: COG0137 Argininosuccinate synthase; KEGG: Os12g0235800; hypothetical protein; K01940 argininosuccinate synthase; SPTR: Q24ZG8 Argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 0.999
SMB91134.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 0.994
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
 0.984
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.967
argJ
N-acetylglutamate synthase /glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.946
SMB83330.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...]
  
 
  0.859
SMB84626.1
Pyruvate carboxylase subunit B; InterPro IPR000891:IPR003379:IPR000089:IPR001882:IPR005776; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; KEGG: hch:HCH_06704 pyruvate carboxylase subunit B; SPTR: B5IWM5 Oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; TIGRFAM: oxaloacetate decarboxylase alpha subunit.
    
 0.858
argR
Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes.
  
  
 0.841
argD
Acetylornithine aminotransferase apoenzyme; InterPro IPR005814:IPR004636; COGs: COG4992 Ornithine/acetylornithine aminotransferase; KEGG: gur:Gura_0226 acetylornithine aminotransferase; SPTR: Q8R7C1 Acetylornithine aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.806
SMB96353.1
Putrescine aminotransferase; InterPro IPR005814; COGs: COG4992 Ornithine/acetylornithine aminotransferase; KEGG: rso:RS04713 putative aminotransferase protein; SPTR: A3S0N2 Acetylornithine aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.794
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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