STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB84910.1InterPro IPR006680:IPR013108; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; KEGG: dde:Dde_0702 chlorohydrolase family protein; SPTR: B9RMA1 Atrazine chlorohydrolase, putative; PFAM: amidohydrolase; Amidohydrolase 3. (453 aa)    
Predicted Functional Partners:
SMB84914.1
Nucleobase:cation symporter-2, NCS2 family; InterPro IPR006043; COGs: COG2233 Xanthine/uracil permease; KEGG: dde:Dde_0701 xanthine/uracil permease family protein; SPTR: A3I5I3 Xanthine/uracil permease family protein; PFAM: Xanthine/uracil/vitamin C permease.
    0.825
SMB93657.1
Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
 
 
 0.757
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
   
  0.702
SMB91517.1
InterPro IPR000836:IPR002375:IPR005904; COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; KEGG: hprT; hypoxanthine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase; SPTR: A1HRR9 Hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.668
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
     
 0.597
SMB95221.1
Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
 
 0.567
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.528
pyrD
Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.493
SMB89707.1
Imidazolonepropionase; SPTR: A1HMK7 Amidohydrolase; PFAM: amidohydrolase; Amidohydrolase 3; InterPro IPR006680:IPR013108; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; KEGG: ccs:CCNA_02050 dihydroorotase.
  
 
 0.487
SMB87792.1
Aspartate/methionine/tyrosine aminotransferase; InterPro IPR001176:IPR004839:IPR004838; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; KEGG: mes:Meso_2719 aminotransferase; SPTR: C1N0Y1 Aspartate/tyrosine/aromatic aminotransferase; PFAM: aminotransferase class I and II.
  
  
 0.484
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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