STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)    
Predicted Functional Partners:
SMB82978.1
TIGRFAM: pyruvate kinase; InterPro IPR015793:IPR008279:IPR015794:IPR018209:IPR001697; COGs: COG0469 Pyruvate kinase; KEGG: dps:DP3116 pyruvate kinase; SPTR: P80885 Pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
 
 0.999
pgk
Phosphoglycerate kinase; InterPro IPR001576:IPR015911; COGs: COG0126 3-phosphoglycerate kinase; KEGG: pca:Pcar_1332 phosphoglycerate kinase; SPTR: Q3AFD1 Phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 
 0.999
gpmI
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.997
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.997
pgi
InterPro IPR001672; COGs: COG0166 Glucose-6-phosphate isomerase; KEGG: gur:Gura_3752 glucose-6-phosphate isomerase; SPTR: Q24VW9 Glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.980
SMB85429.1
InterPro IPR000173:IPR006424; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; KEGG: gsu:GSU1629 glyceraldehyde 3-phosphate dehydrogenase 1; SPTR: A2U8A8 Glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.978
SMB84639.1
InterPro IPR000173:IPR006424; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; KEGG: gsu:GSU1629 glyceraldehyde 3-phosphate dehydrogenase 1; SPTR: A1HQB4 Glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.968
SMB86303.1
Fructose-bisphosphate aldolase; InterPro IPR000771:IPR011289; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; KEGG: dds:Ddes_0131 fructose-1,6-bisphosphate aldolase, class II; SPTR: A1Z6B9 Putative fructose-1,6-bisphosphate aldolase class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase.
  
 0.965
rplD
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
 
 0.945
SMB90274.1
Pyruvate, water dikinase; InterPro IPR008279:IPR002192; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; KEGG: scl:sce4177 phosphoenolpyruvate synthase; SPTR: Q466P7 Phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PRIAM: Pyruvate, water dikinase.
  
 
 0.916
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.