STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB87718.1Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (445 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 0.982
SMB82678.1
InterPro IPR015330; KEGG: dol:Dole_2704 bifunctional DNA primase/polymerase; SPTR: A3V8A1 DNA primase domain protein; PFAM: Bifunctional DNA primase/polymerase.
  
 0.913
SMB96450.1
KEGG: sea:SeAg_B4864 DNA replication protein DnaC; SPTR: A5KLZ8 Putative uncharacterized protein; InterPro IPR001957; COGs: COG1484 DNA replication protein.
  
 
 0.912
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 
 0.906
rplI
LSU ribosomal protein L9P; Binds to the 23S rRNA.
  
  
 0.838
SMB87695.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
 
 0.713
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.683
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 
 0.682
SMB87112.1
InterPro IPR019841; COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: glo:Glov_0365 DNA polymerase III, subunits gamma and tau; SPTR: P09122 DNA polymerase III subunit gamma/tau.
 
 
 
 0.675
SMB87708.1
Uncharacterized conserved protein YybS, DUF2232 family; InterPro IPR018710; COGs: COG4241 membrane protein; KEGG: sat:SYN_00642 hypothetical protein; SPTR: A1HRJ6 Membrane protein-like; PFAM: Protein of unknown function DUF2232, membrane.
       0.673
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.