STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
SMB87843.1Diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR001633:IPR000160; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; KEGG: gme:Gmet_3085 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SPTR: A0YLL7 Putative uncharacterized protein; SMART: EAL domain protein; GGDEF domain containing protein; PFAM: EAL domain protein; GGDEF domain containing protein; TIGRFAM: diguanylate cyclase. (624 aa)    
Predicted Functional Partners:
SMB95186.1
Diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR006674:IPR003660:IPR003607; COGs: COG2206 HD-GYP domain; KEGG: ppr:PBPRA1970 hypothetical protein; SPTR: Q0W2L1 Putative signal transduction protein; SMART: GGDEF domain containing protein; metal-dependent phosphohydrolase HD region; histidine kinase HAMP region domain protein; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; histidine kinase HAMP region domain protein; TIGRFAM: diguanylate cyclase.
0.988
SMB80928.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR013655:IPR000160:IPR000700:IPR000014; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; KEGG: pag:PLES_03351 putative sensory box protein; SPTR: A3L087 Putative uncharacterized protein; SMART: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein.
0.988
SMB79879.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR013655:IPR000160:IPR006674:IPR013767:IPR001610:IPR0036 07:IPR000014:IPR000700; COGs: COG2206 HD-GYP domain; KEGG: pin:Ping_0273 diguanylate cyclase with PAS/PAC sensor; SPTR: A0YVN1 PleD-like protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region; PAS domain containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; metal-dependent phosphohyd [...]
0.987
SMB82971.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR006674:IPR013656:IPR001610:IPR000700:IPR0000 14; COGs: COG2206 HD-GYP domain; KEGG: tdn:Suden_0219 multi-sensor hybrid histidine kinase; SPTR: A1HLT0 Metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; PAS fold-4 domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein.
0.987
SMB88249.1
Diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR001633:IPR000160:IPR003660; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; KEGG: bph:Bphy_0391 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SPTR: A4U5J6 Putative uncharacterized protein; SMART: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; PFAM: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; TIGRFAM: diguanylate cyclase.
 
0.987
SMB78753.1
Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor; InterPro IPR004090:IPR004089:IPR018247:IPR000700:IPR000014; COGs: COG0840 Methyl-accepting chemotaxis protein; KEGG: dde:Dde_1279 methyl-accepting chemotaxis sensory transducer; SPTR: Q3IQX3 Transducer protein htr25; SMART: chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; TIGRFAM: PAS sensor protein.
  
 0.985
SMB89764.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR013656:IPR013767:IPR001610:IPR000014:IPR0007 00; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; KEGG: bja:bll1362 hypothetical protein; SPTR: A0YMH5 PleD-like protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein.
 
0.980
SMB87902.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR013655:IPR000160:IPR013656:IPR000014; COGs: COG2199 FOG: GGDEF domain; KEGG: tau:Tola_1998 diguanylate cyclase with PAS/PAC sensor and hemerythrin-like metal-binding domain; SPTR: A3JDG3 Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); SMART: GGDEF domain containing protein; PAS domain containing protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; TIGRFAM: diguanylate cyclase; PAS sens [...]
 
 
0.977
SMB90328.1
Diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR006674; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; KEGG: gsu:GSU1656 sensory box/response regulator; SPTR: A1HLT0 Metal dependent phosphohydrolase; SMART: GGDEF domain containing protein; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; TIGRFAM: diguanylate cyclase.
 
0.918
SMB85120.1
Diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR000425; COGs: COG2199 FOG: GGDEF domain; KEGG: dde:Dde_1171 diguanylate cyclase; SPTR: A0Y376 Sensory box/GGDEF/EAL domain protein; PFAM: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; SMART: GGDEF domain containing protein.
 
 0.904
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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