STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB88253.1Rod shape-determining protein MreB; InterPro IPR004753:IPR003494; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; KEGG: bba:Bd0211 rod shape-determining protein MreB; SPTR: A1HRE1 Cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; cell division protein FtsA; TIGRFAM: cell shape determining protein, MreB/Mrl family. (339 aa)    
Predicted Functional Partners:
SMB92156.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.979
SMB96298.1
Protein of unknown function; KEGG: gme:Gmet_2681 transcriptional regulator, putative; SPTR: O31771 Uncharacterized membrane protein ymfM.
  
 
 0.876
SMB92166.1
Peptidoglycan glycosyltransferase; InterPro IPR001460:IPR005311:IPR017790; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; KEGG: gme:Gmet_0928 peptidoglycan glycosyltransferase; SPTR: A1HP01 Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
 
 0.839
rodA
Rod shape determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 
 0.814
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.789
SMB89342.1
Iron-sulfur cluster-binding protein; InterPro IPR001450:IPR004017:IPR003741:IPR007087:IPR017900; KEGG: gur:Gura_0152 hypothetical protein; SPTR: A1HPY0 Putative uncharacterized protein; PFAM: protein of unknown function DUF162; protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain.
   
   0.665
SMB89768.1
Cell division protein FtsW, lipid II flippase; InterPro IPR001182; COGs: COG0772 Bacterial cell division membrane protein; KEGG: sfu:Sfum_2588 rod shape-determining protein RodA; SPTR: A1HNZ7 Rod shape-determining protein RodA; PFAM: cell cycle protein; Belongs to the SEDS family.
 
 
 0.628
SMB83330.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...]
  
  
 0.547
SMB92160.1
InterPro IPR007227; KEGG: geo:Geob_3478 rod shape-determining protein MreD; SPTR: A5KLJ4 Putative uncharacterized protein; TIGRFAM: rod shape-determining protein MreD.
  
  
 0.528
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
   0.525
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.