STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB92102.1Formate dehydrogenase iron-sulfur subunit; InterPro IPR001450:IPR017900; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; KEGG: gur:Gura_3387 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: P33389 Protein DVU_0535; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein. (258 aa)    
Predicted Functional Partners:
SMB92103.1
Ni/Fe-hydrogenase 2 integral membrane subunit HybB; InterPro IPR000276; COGs: COG5557 Polysulphide reductase; KEGG: geo:Geob_1636 polysulphide reductase NrfD; SPTR: A4TYL7 Cytochrome Ni/Fe component of hydrogenase-2.
 0.999
SMB83330.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...]
  
 
 0.957
SMB83517.1
4Fe-4S dicluster domain-containing protein; InterPro IPR001450:IPR017900; KEGG: dal:Dalk_1151 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q9P9J2 Polyferredoxin; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
 
 0.869
SMB87924.1
(2Fe-2S) ferredoxin; KEGG: sfu:Sfum_0845 NADH dehydrogenase (quinone); SPTR: B7R2Q5 Respiratory-chain NADH dehydrogenase 51 Kd subunit family.
    
 0.867
SMB91280.1
NADPH-dependent glutamate synthase beta chain; InterPro IPR000759:IPR013027:IPR000103:IPR001557:IPR001327:IPR0014 50:IPR006655:IPR017900:IPR005829; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; KEGG: dat:HRM2_22100 HdrL1; SPTR: Q64DA7 Heterodisulfide reductase subunit A and related polyferredoxins; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
    
 0.862
SMB82202.1
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; KEGG: vfm:VFMJ11_2168 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: A4BEA8 Putative NADH oxidase; InterPro IPR013027:IPR000103:IPR001327:IPR004099:IPR001763; SMART: Rhodanese domain protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein.
   
 0.816
SMB96220.1
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase; InterPro IPR013027:IPR000103:IPR001327:IPR004099:IPR001763; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; KEGG: vpa:VPA0949 putative NADH oxidase; SPTR: A2P2Z9 NADH oxidase, putative; SMART: Rhodanese domain protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein.
   
 0.816
SMB92091.1
[FeFe] hydrogenase, group A; InterPro IPR001450:IPR003149:IPR004108:IPR017900:IPR013352:IPR0063 11; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; KEGG: sat:SYN_01370 iron only hydrogenase large subunit; SPTR: A5KJE2 Putative uncharacterized protein; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: Ferredoxin hydrogenase; TIGRFAM: hydrogenase, Fe-only.
     
 0.784
SMB86776.1
5-methyltetrahydrofolate--homocysteine methyltransferase; COGs: COG1410 Methionine synthase I cobalamin-binding domain; KEGG: geo:Geob_1365 homocysteine S-methyltransferase; SPTR: A5KL27 Putative uncharacterized protein; InterPro IPR006158:IPR003759:IPR003726:IPR000489; PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS.
 
  
 0.772
SMB92022.1
Flavodoxin; InterPro IPR001450:IPR017900:IPR008254; KEGG: gur:Gura_0626 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: Q8PU10 Putative ferredoxin; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
    
 0.748
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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