STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB92194.1Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; InterPro IPR004358:IPR013767:IPR003594:IPR003660:IPR003661:IPR0000 14:IPR005467; COGs: COG5002 Signal transduction histidine kinase; KEGG: gme:Gmet_2694 PAS/PAC sensor signal transduction histidine kinase; SPTR: A1HRU0 Sensor protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; histidine kinase HAMP region domain protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase HAMP region domain prote [...] (588 aa)    
Predicted Functional Partners:
SMB92186.1
Two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP; InterPro IPR001789:IPR001867; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; KEGG: gur:Gura_2556 two component transcriptional regulator; SPTR: A1HRU4 Two component transcriptional regulator, winged helix family; SMART: response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain protein.
 0.989
SMB90688.1
InterPro IPR001789:IPR001867; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; KEGG: gme:Gmet_2693 two component transcriptional regulator; SPTR: P13792 Alkaline phosphatase synthesis transcriptional regulatory protein phoP; SMART: response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain protein.
 0.946
SMB79051.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain; PFAM: response regulator receiver; transcriptional regulator domain protein; InterPro IPR001789:IPR001867; KEGG: dvm:DvMF_0882 two component transcriptional regulator, winged helix family; SPTR: Q7A0U4 Transcriptional regulatory protein srrA; SMART: response regulator receiver; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 0.925
SMB95186.1
Diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR006674:IPR003660:IPR003607; COGs: COG2206 HD-GYP domain; KEGG: ppr:PBPRA1970 hypothetical protein; SPTR: Q0W2L1 Putative signal transduction protein; SMART: GGDEF domain containing protein; metal-dependent phosphohydrolase HD region; histidine kinase HAMP region domain protein; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; histidine kinase HAMP region domain protein; TIGRFAM: diguanylate cyclase.
  
 0.867
SMB80928.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR013655:IPR000160:IPR000700:IPR000014; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; KEGG: pag:PLES_03351 putative sensory box protein; SPTR: A3L087 Putative uncharacterized protein; SMART: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein.
  
 0.857
SMB82917.1
InterPro IPR001789:IPR001867:IPR005829; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; SPTR: A3I5L2 DNA-binding response regulator ResD; SMART: response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pat:Patl_1053 two component transcriptional regulator.
 0.856
SMB89764.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein; InterPro IPR000160:IPR013656:IPR013767:IPR001610:IPR000014:IPR0007 00; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; KEGG: bja:bll1362 hypothetical protein; SPTR: A0YMH5 PleD-like protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein.
  
 0.842
SMB87905.1
InterPro IPR001789:IPR001867; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; KEGG: sat:SYN_00981 response regulator; SPTR: A3I854 Two-component response regulator; SMART: response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain protein.
 0.841
SMB91320.1
InterPro IPR001789:IPR001867; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; KEGG: sat:SYN_00981 response regulator; SPTR: A5KQS3 Putative uncharacterized protein; SMART: response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain protein.
 0.833
SMB89714.1
Two-component system, response regulator, stage 0 sporulation protein F; InterPro IPR001789; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; KEGG: gbm:Gbem_1662 response regulator receiver sensor signal transduction histidine kinase; SPTR: A1HRX1 Response regulator receiver protein; SMART: response regulator receiver; PFAM: response regulator receiver.
 
 0.831
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.