STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB92242.1Purine catabolism regulatory protein; InterPro IPR012914; COGs: COG2508 Regulator of polyketide synthase expression; KEGG: vvy:VV2749 sugar diacid utilization regulator; SPTR: A3I7Y5 Putative uncharacterized protein; PFAM: purine catabolism PurC domain protein. (553 aa)    
Predicted Functional Partners:
SMB85323.1
COGs: COG3835 Sugar diacid utilization regulator; KEGG: sfr:Sfri_2640 transcriptional regulator, CdaR; SPTR: P37047 Carbohydrate diacid regulator.
 
     0.706
SMB92796.1
COGs: COG3835 Sugar diacid utilization regulator; KEGG: msu:MS0694 carbohydrate diacid transcriptional activator CdaR; SPTR: P37047 Carbohydrate diacid regulator.
 
     0.654
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.550
SMB92244.1
Putative heme d1 biosynthesis radical SAM protein NirJ1; InterPro IPR007197:IPR006638; COGs: COG0535 Fe-S oxidoreductase; KEGG: dol:Dole_1225 radical SAM domain-containing protein; SPTR: Q46BK8 Metallo cofactor biosynthesis protein; SMART: Elongator protein 3/MiaB/NifB; PFAM: Radical SAM domain protein.
  
    0.546
SMB92249.1
Transcriptional regulator, AsnC family; InterPro IPR019888; COGs: COG1522 Transcriptional regulators; KEGG: lip:LI0207 transcriptional regulators; SPTR: Q46CH6 Transcriptional regulator, AsnC family; SMART: Transcription regulator, AsnC-type.
  
    0.546
SMB92255.1
KEGG: dal:Dalk_4278 putative transcriptional regulator, AsnC family; SPTR: A1HP62 Putative transcriptional regulator, AsnC family.
  
    0.546
SMB92235.1
InterPro IPR015590:IPR000253:IPR016160; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; KEGG: scl:sce6401 methylmalonate-semialdehyde dehydrogenase; SPTR: Q97YT9 Methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase.
     
 0.484
SMB86791.1
Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily; InterPro IPR002591; COGs: COG1524 Uncharacterized protein of the AP superfamily; SPTR: O29992 Putative uncharacterized protein; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase.
  
     0.426
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.